We have been using Colgate Total Advanced Health mouthwash for about a week now, twice a day. It contains two layer technology: a green and a blue liquid that must be shaken well before each use to activate and mix the two together. The shaking is kind of fun.Watching it settle again is also strangely calming! I found that it takes about 10 second of shaking to get the two liquids mixed well and they separate again after about 30 seconds. Colgate Total Advanced Health mouthwash removes 24 times more bacteria than ordinary, non-antibacterial mouthwashes. 99% of germs are killed on contact.